CD8A and non-small cell lung carcinoma: Compared to NSCLC with stage III, the percentage of CD4+ Tscm, CD8+ Tn and CD8+ Tscm was lower (P< 0.001), and the percentage of CD4+ Tem was higher in NSCLC with stage IV (P = 0.014) (Figure 4A); while the AC of CD4+ Tn, CD4+ Tscm, CD4+ Tcm and CD8+ Tn was significantly lower (P< 0.05) and the AC of CD8+ Tem was higher (P = 0.031) (Figure 4B).