Intriguingly, Zhang Y. M. et al. (2020) established that miR-34a and miR-125a-5p refrained proliferation and metastasis while inducing apoptosis by suppressing the MACC1-mediated PI3K/AKT/mTOR pathway in HCC both in vitro and in vivo. This evidence concerns the gene AKT1 and hepatocellular carcinoma.