CXCL1 and inflammatory bowel disease: Several ELR + CXC chemokines have been identified in association with IBD: CXCL1-2, CXCL5 and CXCL8 chemokines are significantly expressed in areas of intestinal inflammation in patients with IBD compared to normal tissues (Autschbach et al., 2002; Banks et al., 2003; Gijsbers et al., 2004).