The results indicated that FOXQ1 expression was associated with the TMB in 14 tumor types, such as cholangiocarcinoma, colon adenocarcinoma, and esophageal carcinoma, and with MSI in 8 tumor types, such as head and neck squamous cell carcinoma, kidney renal clear cell carcinoma, and thyroid carcinoma. This evidence concerns the gene FOXQ1 and head and neck squamous cell carcinoma.