FOXQ1 and neoplasm: Versican V1 overexpression regulates FOXQ1 and induces tumor cells to secrete chemokine ligand 2, which is able to increase the numbers of tumor-associated macrophages, whereas the inhibition of versican V1 can significantly inhibit FOXQ1 expression (Qian and Pollard, 2010; Xia et al., 2014; Li et al., 2016).