CD4 and inflammatory skin disease: The expression level of AIM2 gene in CD4+ tissue-resident memory T (CD4+ Trm) cells was measured in the patients with acute cutaneous lupus erythematosus (ACLE), subacute CLE (SCLE), localized discoid lupus erythematosus (localized DLE), psoriasis, and other inflammatory skin diseases (Zhao et al., 2022).