In addition, COL5A1 up-regulation predicted dismal prognostic outcome in renal clear cell carcinoma (RCCC), BC, OC, and gastric cancer (GC) (Feng et al., 2019; Wei et al., 2020; Zhao et al., 2020; Zhang et al., 2021b). Here, COL5A1 is linked to clear cell renal carcinoma.