Moreover, α-fetoprotein (AFP), a fetal serum protein, is the gold standard for surveillance of HCC and occurs mainly in the development of HCC or germ cell tumors (El-Bahrawy, 2010; Tzartzeva et al., 2018), providing more clues that LINC02475 might exhibit a huge advantage as a biomarker like AFP in HCC diagnosis and prognosis evaluation based on the restricted expression of LINC02475 toward normal testis. This evidence concerns the gene LINC02475 and hepatocellular carcinoma.