The proportion of patients in the recurrence group with PVTT, medium and high degree of differentiation, combined with vascular invasion, serum AFP level ≥ 400 ng/dL, multiple tumors, maximum diameter ≥ 5 cm, combined with cirrhosis, and polynodules was higher than that in the nonrecurrence group; the differences were statistically significant (all P < 0.05), as shown in Table 3. The gene discussed is AFP; the disease is Cirrhosis.