Compared with the chronic status of hyperglycemia, acute hyperglycemia is associated with greater oxidative stress, an increase in inflammatory factor levels, and neurohormonal derangements such as excessive elevations of glucagon, epinephrine, cortisol, tumor necrosis factor-α (TNF-α), and interleukin-1 levels (Dungan et al., 2009). The gene discussed is GCG; the disease is Hyperglycemia.