Based on multivariable Cox analysis, the expression of PER-1 (HR=0.94, 95% CI=0.90-0.98, P=0.06), CRY2 (HR=0.095, 95% CI=0.91-0.98, P=0.003), and NPAS2 (HR=1.19, 95% CI=1.03-1.38, P=0.021) were independent prognosis biomarkers of HCC survival, which can be seen in the Forest plots in Figure 5. Here, NPAS2 is linked to hepatocellular carcinoma.