We speculate that the high expression of these immune-related genes can alleviate the aggravation of COVID-19 symptom severity, such as GAGE12F, TNMD, MAGEA6, MAGED2, and XAGE1A (Tanzarella et al., 1999; Tolppanen et al., 2008; Vujanovic et al., 2014). This evidence concerns the gene MAGED2 and COVID-19.