Among them, the enrichment of HBV-DNA integration in TERT, CCNE1, and CCNA2 genes in tumoral samples has also been confirmed by analyzing the publicly available database VISDB, collecting 20558 HBV-DNA integration sites in tumor/peritumor/non-tumor liver samples from 45 publications (Tang et al., 2020). Here, CCNA2 is linked to neoplasm.