MYD88 and familial pancreatic carcinoma: Although the production of MyD88-dependent IL-12 is essential to resist T. gondii infection (LaRosa et al., 2008), MyD88 is not necessary for the anti-tumor response of B16F10 melanoma (Baird et al., 2013a) and ovarian cancer (Fox et al., 2016), but is required for pancreatic cancer (Sanders et al., 2015).