Although the production of MyD88-dependent IL-12 is essential to resist T. gondii infection (LaRosa et al., 2008), MyD88 is not necessary for the anti-tumor response of B16F10 melanoma (Baird et al., 2013a) and ovarian cancer (Fox et al., 2016), but is required for pancreatic cancer (Sanders et al., 2015). The gene discussed is MYD88; the disease is neoplasm.