CUBN and infection: Because submicroscopic malaria should be considered not only a continuous antigenic stimulus for a pool of protective Igs but also the main infectious reservoir (Biswas et al., 2014), our results together with other similar studies (Bousema et al., 2014) underscore the need to properly monitor and diagnose submicroscopic infections, as they are often asymptomatic (Biswas et al., 2014; Niang et al., 2017) and constitute the most common Plasmodium infection in endemic areas (Katrak et al., 2017).