CRP and infection: Therefore, in the present study, we tested the correlations between sEng and other biomarkers in an attempt to estimate for the first time a link between elevated sEng and other factors [infection (leukocytes, CRP); organ failure (creatinine, bilirubin, the Horowitz index); circulatory failure (catecholamine dose, lactate); severity of condition (SOFA, Lung injury severity score)].