BCHE and neuroblastoma: The above shifts in the balance between the variants called for further exploring the regulation of individual cholinesterase variants in non-diseased neurons, for which purpose we employed cultured human-derived LAN-5 (Figure 5A) and SH-SY5Y (Figure 5B) neuroblastoma cells of male and female origin, respectively, as an in vitro model of cholinergic neurons’ differentiation.