BCHE and Alzheimer disease: In addition, SNPs in the non-coding 5′-untranslated region (5′-UTR) (rs1126680) and intron 2 (rs55781031) of the BCHE gene may play as yet undiscovered roles in the emergence and progression of AD and PD (Rösler et al., 2018; Jasiecki et al., 2019).