Then, IHC staining of SELENBP1 in colorectal NTs and CRCs in the HPA database indicated that SELENBP1 was distributed diffusively in the nuclei and cytoplasm and on the membrane, and its expression was significantly lower in tumor cells than in glandular cells (p < 0.0001; Figure 3c and d). This evidence concerns the gene SELENBP1 and neoplasm.