Consistently, in genetic type 2 diabetic rodent models [e.g., Goto‐Kakizaki (GK) rats or Otsuka Long‐Evans Tokushima Fatty (OLETF) rats], a slow‐to‐fast transition of MHC isoforms in skeletal muscle has been observed (Yasuda et al., 2002, 2006). Here, HLA-C is linked to type 2 diabetes mellitus.