Compared with individuals at low CRP concentration, those in the intermediate and high CRP concentration had a higher risk of overall cancer, with HRs of 1.05 (95%CI: 1.02, 1.07; P < 0.001) and 1.15 (95%CI: 1.12, 1.18; FDR-adjusted P < 0.001), respectively (Table 3). This evidence concerns the gene CRP and cancer.