Furthermore, we examined the expression profiles of previously unreported model genes (MPZ, SCARA3, MPP2 and PBXIP1) in clinical samples from CRC patients by qPCR (Fig. 9A-D) and IHC (Fig. 9E-H) analysis and found that the expression levels of MPZ, SCARA3, MPP2 and PBXIP1 were high in CRC tissues. This evidence concerns the gene PBXIP1 and colorectal carcinoma.