Most of these proteins are essential modulators of cellular protein‐RNA condensate formation, including SGs, P bodies, and P granules, etc. Abnormal DDXs expression is associated with cancer development, proposing them as attractive targets for cancer therapy.[178, 276] In particular, the DDX3X inhibitors RK‐33 and NZ51, the eIF4A inhibitors silvestrol, hippuristanol, CR‐1‐31‐B, and pateamine A, and the phosphorylated DDX5 inhibitor RX‐5902 exhibit anti‐cancer activity.[277] However, whether their anticancer activity is linked to condensates regulation needs to be further explored. This evidence concerns the gene DDX3X and cancer.