When phenylalanine in the chimeric FG repeats is substituted with serine, NUP98‐HOXA9 abolishes IDRs and loses LLPS and tumorigenic activity (Figure 7B).[246] In line with this observation, other leukemogenic NUP98 fusions also recruit similar transcriptional machinery into biomolecular condensates.[247] Furthermore, the oncogenic TF FUS‐CCAAT/enhancer binding protein homologous protein (CHOP) is localized in small nuclear puncta and colocalizes with the SE marker BRD4 in myxoid liposarcoma.[248]. Here, NUP98 is linked to myxoid liposarcoma.