Given the critical role of EMT induction in tumor progression, the authors also assessed the expression levels of EMT-associated genes in these cells and observed significantly reduced expression of E-cadherin following LHX1 overexpression and a concomitant rise in expression levels of Slug, Snail, Vimentin, and N-cadherin (Fig. 4G). This evidence concerns the gene SNAI1 and neoplasm.