A similar phenomenon was observed by Arts et al. [190] where the coculture of monocytes from a healthy donor with thyroid cancer cells resulted in differentiated macrophages displaying a metabolic transcriptomic signature with increased glycolysis and activation of the AKT1/mammalian target of rapamycin (mTOR) pathway, an essential regulator of cell metabolism [190]. This evidence concerns the gene MTOR and thyroid gland carcinoma.