The Parametric Gene Set Enrichment Analysis (PGSEA) showed commonly activated KEGG pathways between converted and primary cells when compared with miPSCs were “mmu05200: Pathways in cancer”, “mmu04510: Focal adhesion”, “mmu04390: Hippo signaling pathway”, “mmu04512:ECM-receptor interaction”, “mmu04310:Wnt signaling pathway”, and “mmu04151:PI3K-Akt signaling pathway”, which were apparently related with cancer. This evidence concerns the gene AKT1 and cancer.