Previous studies suggest that abnormal ASF1B expression contributes to the occurrence and progression of different cancers, including cervical cancer (CC), thyroid cancer (TC), breast cancer (BC), prostatic cancer (PCa) and lung cancer (LC) (Liu et al. 2020; Corpet et al. 2011; Ma et al. 2021; Zhang et al. 2021; Han et al. 2018). The gene discussed is ASF1B; the disease is breast carcinoma.