PRPF3 and allergic disease: For cg26851984, which was identified as a mediator of the association between maternal smoking during pregnancy and sensitization with DACT, we identified the closest gene to be PRPF3. This gene is associated with eczema [13], eosinophil counts [47] and any allergy [15], supporting the importance of this CpG as a mediator of allergen sensitization.