The top nine pathways with enrichment in the GTF2I mutant group were the adherens junction, dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, vascular smooth muscle contraction, basal cell carcinoma, melanogenesis, Notch signaling pathway, transforming growth factor (TGF) beta signaling pathway, and wingless/integrated (WNT) signaling pathway (Fig. . Here, GTF2I is linked to arrhythmogenic right ventricular cardiomyopathy.