COL1A1 and Hepatic fibrosis: Liver fibrosis was mostly not observed, as shown by the histological analyses with reduced mRNA levels of fibrogenic markers, including alpha smooth muscle actin (α-Sma), collagen type 1 alpha 1 (Col1a1), metalloprotein-3 (Mmp-3), and transforming growth factor beta (Tgfβ) (Fig. 3i–k).