UCP1 and metabolic dysfunction-associated steatohepatitis: Notably, KY19334 promoted browning of scWAT, as shown by the specific induction of mitochondrial biogenesis markers, including thermogenin uncoupling protein 1 (UCP1) and beige-fat markers, which were reduced in HFD + CCl4-induced NASH in mice (Fig. 4g, h).