LRRK2 and Parkinson disease: To assess whether PD-causing LRRK2 dysfunction causes downstream effects on the normal multimerization of αSyn, we obtained iPSCs derived from two unrelated PD patients harboring the G2019S mutation from the Stem Cell Engineering facility at CMCB (Technische Universität Dresden), referred to here as G2019S L1 and G2019S L235.