To ascertain whether induction of CD8 T cell infiltration was connected to increased levels of autophagic flux upon IM + anti-VEGF treatment, we silenced the expression of ATG3, a key regulator of autophagy, in glioma-derived cells, which were implanted into the brains of immunocompetent animals (Figures S2M and S2N). This evidence concerns the gene CD8A and central nervous system cancer.