The literature shows thatC. albicans is implicated in oral diseases, including caries,2 periodontitis,38 denture stomatitis,39 and endodontic lesions.40 We suggest that there is a synergistic relationship between the receptor for SARS-CoV-2 entry (ACE2) andC. albicans/A. The gene discussed is ACE2; the disease is mouth disorder.