Comparing S. irisin levels between BD patients with and without ocular lesions and vascular events revealed no significant differences (32.69.3, 30.96.1 P = 0.5) (32.0 6.67, 32.18.92 P = 0.8), whereas patients with neurological deficits had significantly lower S. irisin levels than those without neurological deficits (27.24.2, 32.6 8.5 P = 0.04). The gene discussed is FNDC5; the disease is Behcet disease.