The correlation analysis for ARC revealed that the ODI values of nodes 72-73 were positively correlated with FINS and HOMA-IR in T2DM patients, and the ICVF values of node 13 were negatively associated with FBG, which suggests that the insulin level and insulin resistance may be a factor in the dispersion of the axonal orientation and that glucose status may be associated with the axonal density of the right ARC. This evidence concerns the gene INS and type 2 diabetes mellitus.