(f–h) Hematoxylin and eosin (H&E) staining for pathological changes (f) anti-Cleaved-Caspase 3 immunohistochemical staining for apoptosis (g) and anti-Ki-67 immunohistochemical staining for cellular proliferation (h) at different depths (1.5, 3, 4.5, 6, and 7.5 mm) of dissected STS26T tumor tissues from the NIR-III (0.5 W cm–2, 5 min) group and the NIR-III (1 W cm–2, 5 min) group. Here, CASP3 is linked to neoplasm.