When assessing these nuclear abnormalities on a quantitative level, a significantly increased proportion of both N. caninum-infected (18.8 ± 6.9%) and non-infected (81.2 ± 6.9%) cells within an infected cell layer (infection rate: 25.96 ± 14.73%) showed inadequate lamin B1 distribution patterns and misshaped nuclei (Figure 6B) when compared to cells from non-infected cell layers (9.3 ± 2.8%) (infected/non-infected cells from infected layer vs. non-infected cell layer: both p = 0.0078). The gene discussed is LMNB1; the disease is infection.