ULK1 and cardiac arrhythmia: Interestingly, in a transgenic Drosophila melanogaster model mimicking human cardiomyopathy, overexpression of Atg1 eliminated aggregates of mutant lamin C and reduced cardiac arrhythmia, suggesting that enhanced autophagy activity and processing of lamins A and C are beneficial for cell and tissue homeostasis (Bhide et al., 2018).