The indicators for predicting DSS in patients with stage IIIC breast cancer included ER status, PR status, molecular typing, T stage, LNP number, and LNR (P ≤ 0.001, P ≤ 0.001, P ≤ 0.001, P ≤ 0.001, P=0.002, and P ≤ 0.001, respectively; Table 4). The gene discussed is ESR1; the disease is breast cancer.