ZFP36 and malignant colon neoplasm: Interestingly, a recent study has revealed that ZFP36 can directly bind interleukin- (IL-) 23, cyclooxygenase- (COX-) 2, and VEGF in the 3′-UTRs, thereby reducing the stability and expression in colon cancer and ZFP36 depletion results in colon cancer cell proliferation [30].