TNNI3 and dilated cardiomyopathy: Furthermore, our RNA-seq analysis showed that knockdown of CD36 resulted in downregulation of the expression of genes associated with the “dilated cardiomyopathy”, “hypertrophic cardiomyopathy (HCM)” and “ cardiac muscle contraction” pathways, such as Myh6, Myh7, Tnni3 and Cacng6, in skeletal muscle cells, suggesting that CD36 may have an important regulatory role on skeletal muscle gene expression.