In conclusion, based on the data in vitro and in vivo using a panel of cervical cancer cell lines and nude mice, we provided compelling evidence that Mzb monotherapy can suppress proliferation and induce apoptosis and enhance the cytotoxic effect and apoptosis induced by CDDP in combination by strengthening Ang-1, inhibiting Tie-2 expression in the Ang-1/Tie-2 signaling pathway, and inhibiting the Flt-3/Flt-3L and SCF/c-Kit proliferative signaling pathways. Here, KIT is linked to cervical carcinoma.