We then carried out topological 10 CRGs interaction network analysis in the merge cohort (Figure S1A), and then Kaplan-Meier survival analyses showed that among the 10 CRGs, 9 CRGs were significantly correlated with overall survival in HCC patients except for FDX1, which was not correlated with overall survival (Figure S1B–J). This evidence concerns the gene FDX1 and hepatocellular carcinoma.