Found that many important cancer-related pathways (such as “Central carbon metabolism in cancer”, “PL-L1 expression and PD-1 checkpoint” and “RIG-I-like receptor signaling pathway”, as well as “VEGF signaling pathway”, “Toll-like receptor signaling pathway” and “Cysteine and methionine metabolism”) were intervened by the exercise-regulated miRNAs, especially the immune- and metabolism-related pathways (Figure 3D). This evidence concerns the gene VEGFA and cancer.