PTEN and neoplasm: One “probably damaging” ERCC6 mutation (as predicted by PolyPhen2 tool, being of unknown significance in the ClinVar database) was present in the tumor sample of one uterine LMS patient, and one MLPS patient’s tumor harbored both one pathogenic (ClinVar) PTEN mutation, and one PIK3CA mutation (possibly damaging, according to PolyPhen-2).