There is no evidence that the gut microbiota plays an important role in the development of SLE through AhR pathways, and Adriana Cuervo’s group first demonstrated the presence of gut microbial dysbiosis in SLE patients (129), and it has even been suggested that new biomarkers of SLE may be found in the human microbiota (130). Here, AHR is linked to systemic lupus erythematosus.