AHR and systemic lupus erythematosus: Kanyarat Udompornpitak et al (160) used the AhR agonist 1,4-chrysenequinone (1,4-CQ) to produce a strong response in macrophages of FcgRIIb-/- mice compared to macrophages of wild-type mice, and these activations led to a more severe inflammatory response, causing FcgRIIb-/- mice to develop lupus-like features (161).