Recent scRNA-seq data (13) showed that the T17 cell subset that most conforms to current concepts of pathogenic Type 17 T-cells in human psoriasis skin (23, 25, 27, 31) was the IL-17A+ IFNγ+ T17 cell subset, synthesizing high levels of TNF, IL-26 and IL-36G. This evidence concerns the gene IL17A and psoriasis.