AGT and type 2 diabetes mellitus: In the RENAAL (Reduction in End Points in Noninsulin-Dependent Diabetes Mellitus with the Angiotensin II Antagonist Losartan) study, the albuminuria reduction rate at 6 months showed that 41.6% of patients experienced no reduction in albuminuria; in 25.9%, albuminuria was lowered by 0–30%, and 32.3% saw an albuminuria decrease of over 30% [19].