NR4A3 and atherosclerosis: Recent studies had reported that platelet-derived growth factor (PDGF), which plays a critical role in the pathogenesis of atherosclerosis, can induce the expression of NOR1 in a manner dependent on ERK1/2-MAPK and CREB signaling, and that the increased NOR1 can mediate the subsequent proliferation of VSMCs (Martínez-González et al., 2003; Bi et al., 2013) (Figure 4; Table 1).