NR4A3 and neoplasm: In tumor pathogenesis, NOR1 shows a negative correlation with tumor progression, and enhanced NOR signaling is able to suppress tumor cell growth (Shipp et al., 2002; Mullican et al., 2007; Ramirez-Herrick et al., 2011; Boudreaux et al., 2012; Deutsch et al., 2017; Zhang et al., 2018; Boudreaux et al., 2019; Fedorova et al., 2019; Haller et al., 2019; Son et al., 2019; Wang et al., 2020; Safe and Karki, 2021).