The AML-like symptoms caused by Nur77/NOR1 gene deficiency might be related to the increased expression of MYC, an oncogene whose expression is closely related to the pathogenesis of AML and which might be strongly suppressed by NOR1 in a Nur DNA-binding manner (Boudreaux et al., 2012). The gene discussed is MYC; the disease is acute myeloid leukemia.