Researchers have found that the expression levels of NOR1 are remarkably increased in proliferated and remodelled vessels (Rodríguez-Calvo et al., 2013; Martínez-González et al., 2021), suggesting that NOR1 may be a risk factor for promoting cardiovascular diseases that are closely associated with inflammation (Hafiane and Daskalopoulou, 2022). The gene discussed is NR4A3; the disease is cardiovascular disorder.