The enrichment analysis results of the KEGG pathway mainly involved neuroactive ligand-receptor interaction, serotonergic synapse, dopaminergic synapse, cAMP signaling pathways, calcium signaling pathways, Alzheimer’s disease, lipid and atherosclerosis, prolactin signaling pathways, Gap junction, morphine addiction, Parkinson’s disease and other pathways. This evidence concerns the gene PRL and Alzheimer disease.