Adjusted for family history of CHD, age, years of smoking, SBP and total and HDL cholesterol level, anxiety due to the overlap between depression and anxiety disorder, atypical including albumin, high-sensitivity C-reactive protein, education levels, diastolic BP, pulse rate, BMI, LDL cholesterol, 10 year changes in mobility, alcohol use, triglycerides, and medication use. This evidence concerns the gene ALB and depressive disorder.