Overall, 11.5% (14/122) of all 46, XY DSD patients were found to carry P/LP variants in more than one gene known to be associated with DSD (ANOS1, AR, BBS7,CHD7, FGFR1, FGFR3, FLNA, GPC3, HOXA13, KAT6B, LHCGR, NRAS, NR5A1, OFD1, PRKAR1A, PROK2, PROKR2, RXFP2, SEMA3A, SHH and SRD5A2). Here, NRAS is linked to disorder of sexual differentiation.